SPORIDEX PLUS HP-1
SPORIDEX PLUS HP-1 cold sterilizing agent, based with a 10% of potentiated acid Glutaraldehyde and activated with a specific nonionic agent. Registered with Italian Ministry of Health N. 9553.
SPORIDEX PLUS HP-1 is particularly indicated for disinfection of:
surgical istruments, anesthetic equipments, endospopy, surgical vacuums, etc... used with an average dilution of 20% (1 + 4 parts water) equal solution of 2% Glutaraldehyde.
For general disinfecion of habitat, public places, a dilution of 5% (1 + 19 parts water) equal to solution of 0,5% Glutaraldehyde, via nebulization or dampening the surfaces interested.
Sporidex Plus HP-1 is already activated, it functions in an acid habitat, it has a pH of 5,5 when concentrate and a pratically unaltered stability even after 2 years; diluted to 2% maintains a pH of 6,2 after 12 months, therefore still efficient.
From our experience we advise, however not to utilize diluted product of over 60 days, thus respecting the good norm of not using solutions in which Resistent Bacteria could have generated.
Since 1962, reams of literature has been written on the properties of Glutaraldehyde at 2% first in watery alkaline solution (to activate), then in 1971 on acid watery solution (already activated). Literature more or less scientific, more or less independant, or interested edited principally in America and recently even in Italy.
We limit this impossible list to a wise constatation by Robert R. Runnels (1) appeared in a recent volume on the control of infection, edited in Italy, chapter “Conclusion”, of a relation, less recent, by R. M. G. Boucher (2) appeared in America and relative to Pentanedial.
(1) - From the moment that microbiotic life can only be seen through a microscope, the control of infection is a science of “faith”. Besides the use of biological monitors, (check ups) the results of infection control procedure are rarely seen.
This lack of visibility therefore makes the choice of procedures and products extremely important.
If the procedures or products do not operate as declared, an infection may come about, and patients and dental staff pay the consequences. When we accept advices or instructions on the control of infection, we should know the validity of the instructor. When products are purchased for the control of infection, the scientific pubblications should be read, and they must be INDEPENDANT, besides the in-formations which sustain the affermations stated, should be read.
(2) - If one were to review the history of “chemical sterilization”, three important landmarks would stand out.
- first would be the use of formaldehyde solutions in the 1920’s
- second the development of ethylene oxide technology
- in the late 1930’s, and last but not least Pepper's discovery in 1962 of the sterilizing characteristics of alkaline saturated dialdeydes.
Only two of these chemicals are currently used as sterilant solutions, but formaldehyde is severely limited by its slowness and toxicity while alkaline Pentanedial is handicapped by a short two week life and a poor stability.
The appearance of potentiated acid 1,5 Pentanedial solution may provide a long-awaited answer for an aqueous sterilant with the following characteristics:
1) fast and wide spectrum biocidal action
2) long active life
3) extreme stability under aging or heating conditions
4) insignificant residuals after proper processing
5) low corrosion level and
6) moderate toxicity to users
When combined with ultrasonic irradiation, the new product will also provide many answers to sterilization problems which today are handled with toxic gases or deleterious heat. The sonosyner-gistic approach will definitely sterilize heat-sensitive instruments in less than 30 minutes while also eliminating the need for lengthy deaeration periods. Basic research is presently being conducted at the Walter Reed Hospital to define accurately the relationship between temperature, acoustic energy level and contact time to achieve sterilization in liquid phase according to EPA standards. In short, a new look at the fundamentals behind cidal activity of a relatively old product has led to the discovery of one of the most promising tools against bacteriological contamination. Hospitals and other healt care facilities will be the first to benefit from this development.
(A) Robert R. Runnels, D.D.S. Professor of the Department of Patology, School of Medicine, University of Utah, U.S.A. - Febbraio 1985 «controllo dell'Infezione negli studi Odon-toiatrici» Edito da I.TATE. Dolo (VE) per D.I.S. sas Lecco (CO).
(B) R.M.G. Boucher, 0 il presidente del «Wave Energy Systems, Inc. - 600 Madison Avenue, New York - autore di: «Potentiated acid 1,5 Pentanedial solution - a new chemicals sterilizing and disinfecting agent». American Journal of Hospital Pharmacy 31:546-557 (June 1974).